Meso-relle Mesotherapy needles are extremely thin, with precise sharpening, so patient discomfort is very minimal. Mesotherapy is one of the most sought-after facial treatments in recent years and works by injecting ingredients into the mesoderm, the middle layer of the skin, using very fine and specially designed needles. They are individually sterilized, in blister packs, are single-use, and have a cap that covers the needle before and after use to prevent injuries. They are made in Italy. Bases for the needles are also available, circular or linear 3 & 5 positions.